Our San Diego research facility (ChemBridge Research Laboratories, Inc.) is focused on ultra-fast turn-around hit-to-lead libraries. The facility has the capacity to produce and deliver up to 40,000 compounds per year with a majority of the libraries produced in 1 week. Between March - June 2008, close to 90% of the libraries produced in San Diego were done in 1 week.
Properties
Some characteristics of our Ultra-Fast Libraries:
 |
Library size is 50-500 delivered compounds |
 |
 |
Avg. passing rate is 65% |
 |
Avg. number of steps done in parallel is 2 (range 1-5) |
 |
Avg. µmol amount for delivered compounds is 25 µmol (range 3-50 µmol) |
 |
All compounds are purified by HPLC |
 |
All compounds are analyzed by LCMS/ELSD or UV Purity requirements are up to the client. |
 |
Multi-step synthesis of intermediates in avg. 5 g amount (range 1-20 g) when required. |
 |
Protocol development when required |
 |
Library design is done by the client |
 |
Templates provided by the client or acquired commercially |
 |
Reagents provided or reimbursed by the client |
Experience
ChemBridge Research Laboratories, Inc.:
 |
State-of-the-art technology refined over 7 years of collaborations with Merck, Pfizer, AstraZeneca, others |
 |
Rapid development of parallel synthesis protocols (high Ph.D. ratio (77%) & proven problem solving abilities) |
 |
Multi-step synthesis of intermediates and templates up to 20 g on-the-fly, synthetic skills versatility |
 |
Virtually any chemistry at ≥ -20°C can be performed |
For more information contact:
Email: Ultrafast-libraries@chembridge.com
Phone: (858) 451-7400 x170
US Toll Free: (800) 964-6143 x170
top of the page |