Our San Diego research facility (ChemBridge Research Laboratories, Inc.) is focused on ultra-fast turn-around hit-to-lead libraries. The facility has the capacity to produce and deliver up to 40,000 compounds per year with a majority of the libraries produced in 1 week. Between March - June 2008, close to 90% of the libraries produced in San Diego were done in 1 week.

Properties

Some characteristics of our Ultra-Fast Libraries:

	Library size is 50-500 delivered compounds
	Avg. passing rate is 65%
	Avg. number of steps done in parallel is 2 (range 1-5)
	Avg. µmol amount for delivered compounds is 25 µmol (range 3-50 µmol)
	All compounds are purified by HPLC
	All compounds are analyzed by LCMS/ELSD or UV Purity requirements are up to the client.
	Multi-step synthesis of intermediates in avg. 5 g amount (range 1-20 g) when required.
	Protocol development when required
	Library design is done by the client
	Templates provided by the client or acquired commercially
	Reagents provided or reimbursed by the client

Experience

ChemBridge Research Laboratories, Inc.:

	State-of-the-art technology refined over 7 years of collaborations with Merck, Pfizer, AstraZeneca, others
	Rapid development of parallel synthesis protocols (high Ph.D. ratio (77%) & proven problem solving abilities)
	Multi-step synthesis of intermediates and templates up to 20 g on-the-fly, synthetic skills versatility
	Virtually any chemistry at ≥ -20°C can be performed

For more information contact:
Email: Ultrafast-libraries@chembridge.com
Phone: (858) 451-7400 x170
US Toll Free: (800) 964-6143 x170

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