Chemistry Services

High-end, research-intensive custom library and synthetic chemistry services

Custom/Exclusive Chemical Libraries

ChemBridge Corporation is engaged in the research, development, and production of custom chemical libraries on an exclusive basis for selected partners. These chemical libraries leverage the advanced, chemistry-focused, proprietary technology platform that was first developed by ChemBridge for the generation of novel commercial libraries based on ChemBridge proprietary scaffolds. This platform now matches the most challenging quality standards of the world's leading pharmaceutical companies and enables us to deliver custom chemical libraries within our partners’ demanding timelines.

Our advanced and flexible chemistry-focused proprietary technology platform enables us to utilize effectively our synthetic, medicinal, and computational chemistry resources to successfully design and produce a wide range of diverse, targeted, focused chemical libraries or follow-up and hit-to-lead chemical libraries. We are able to generate chemical libraries to all our partners’ varied requirements of scale, purity, and formats.

ChemBridge has established itself a premier provider of custom library services, having signed into major multi-year agreements to develop and supply exclusive custom libraries to Pfizer, Inc., Merck & Co., Inc., AstraZeneca and many others. Our successful track record provides further proof of the value of our technology and capabilities.

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Custom Synthesis

Do you need synthesis or re-synthesis of specific building blocks, monomers or scaffolds? Or synthesis of fragments, leadlike or druglike compounds or analog/SAR sets?

ChemBridge has more than a decade of experience synthesizing exclusive and non-exclusive building blocks, scaffolds, individual compounds and parallel-synthesized libraries. We are able to quote on a wide range of projects from mg to gram and higher scale. Compounds are synthesized to your specifications and analytical requirements. For larger projects, ChemBridge offers fee-for-service and FTE based collaborations.

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Example Custom Synthesis Projects

  • Custom building blocks, monomers, scaffolds or fragments
  • Synthesis or re-synthesis of leadlike or druglike compounds from ChemBridge or other sources or from published articles
  • Analogs for SAR studies or hit explosion
  • Hit to Lead libraries requiring individual compound synthesis or parallel synthesis


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